Esketamine (brand name Spravato®) is an FDA-approved nasal spray medication used in the treatment of treatment-resistant depression (TRD). Unlike traditional antidepressants that work on serotonin, norepinephrine, or dopamine, esketamine targets the brain’s glutamate system, which helps restore healthy brain connections linked to mood and emotional regulation.
Esketamine (brand name Spravato®) is an FDA-approved nasal spray medication used in the treatment of treatment-resistant depression (TRD). Unlike traditional antidepressants that work on serotonin, norepinephrine, or dopamine, esketamine targets the brain’s glutamate system, which helps restore healthy brain connections linked to mood and emotional regulation.
At SNBCare, we offer FDA-approved Esketamine (Spravato®) therapy for adults with treatment-resistant depression.
Process: Starts with a full evaluation → personalized plan → in-clinic nasal spray sessions (about 2 hours each) → ongoing monitoring and support.
At SNBCare, we believe that every treatment journey should be personalized, supportive, and built on evidence-based care. Here’s what you can expect when starting
Your journey begins with a comprehensive assessment by our experienced psychiatric providers. We review your medical history, previous treatments, and current symptoms to determine if Esketamine is the right option for you.
If you’re eligible, we design a customized care plan that fits your needs. This includes dosage selection, scheduling of in-office sessions, and integration with your ongoing therapy or medications.
During each session, we monitor your vital signs, response, and comfort level. After treatment, you’ll remain under observation before returning home. We continuously track your progress and adjust the plan as needed.
Esketamine therapy is designed for people living with treatment-resistant depression (TRD), individuals who have not improved after trying two or more antidepressants. While its primary FDA approval is for TRD, ongoing research and clinical experience suggest potential benefits in related mental health conditions when standard treatments aren’t enough.
Esketamine offers new hope for people living with depression that hasn’t responded to traditional medications. At SNBCare, patients often experience meaningful improvements in both symptoms and daily functioning.
Many patients notice a reduction in depressive symptoms within days to weeks, compared to the longer wait times of traditional antidepressants.
Esketamine helps restore healthy brain connections, leading to more balanced emotions and fewer depressive episodes.
As mood improves, patients often report greater focus, motivation, and energy, making it easier to return to work, school, and personal activities.
Clinical studies show esketamine can help prevent recurrence of major depressive episodes, especially when combined with ongoing therapy or oral antidepressants.
The ultimate goal is more than symptom control, it’s helping you feel like yourself again, rebuild relationships, and enjoy life with greater resilience.
Book your personalized consultation today and take the first step toward healing with SNBCare’s expert team.
Adults with Treatment-Resistant Depression (TRD)
Individuals with Major Depressive Disorder (MDD) experiencing persistent symptoms
Patients with co-occurring anxiety symptoms that do not fully respond to medication or therapy.
People at risk of relapse who need additional support beyond oral antidepressants.
Esketamine is approved for adults 18 and older.
It is used when therapy or oral medications alone aren’t providing enough relief.
Patients are carefully screened by providers to ensure safety and eligibility before starting treatment.
Fill out the form to schedule a Esketamine Consultation
Fill out the form to schedule a Esketamine Consultation
Some patients notice improvements in mood and energy within 24–72 hours of their first few treatments. For others, it may take several weeks. Everyone responds differently, but esketamine often works faster than traditional antidepressants.
If you don’t experience improvement, our team will carefully review your treatment plan. We may adjust your dosage, explore other medications, or combine esketamine with therapy or alternative approaches tailored to your needs.
Temporary side effects can include dizziness, nausea, mild dissociation, or an increase in blood pressure. These usually resolve within 1–2 hours. Our staff monitors you closely during each session to ensure your safety.
Absolutely. Esketamine works best as part of a comprehensive treatment plan that may include therapy, lifestyle support, and oral antidepressants. We often coordinate care with your therapist or primary provider.
Yes. While esketamine must be administered in person at our clinic, we provide telepsychiatry follow-ups for progress checks, medication management, and ongoing support between visits.
