What is the difference between Esketamine (Spravato) and Ketamine Infusion?
- Esketamine is a chemically similar compound to Ketamine but structurally different. Ketamine is used for anaesthesia and pain relief, whereas Esketamine is used for resolution of depressive symptoms in those who have seen no improvement while using two or more antidepressants. It is derived from the same compound as Ketamine but is used at a much lower dose.
- Ketamine Infusion is not covered by insurance and is paid out of pocket, Esketamine Therapy is covered by all major insurances.
What are the side effects of Esketamine Therapy?
- Certain side effects, as with all forms of treatment, are rare but to be expected as a risk in all instances.
- The most common side effects of Esketamine occur and resolve on the same day as treatment. These include, but are not limited to:
- Sedation, Dissociation, Dizziness, Nausea, vomiting, difficulty breathing, Vertigo, Hypoesthesia, Anxiety, and raised Blood Pressure,
What are the risks of Esketamine Therapy?
- The risks involved with Esketamine therapy coincide with your medical history. Those who have a history of the following are not recommended for Esketamine Therapy.
- Stroke/Intracerebral Haemorrhage
- Aneurysmal vascular disease → this includes thoracic abdominal aorta, intracranial and peripheral arterial blood vessels, and arteriovenous malformations
- History of allergic reactions or anaphylaxis to Esketamine or Ketamine
- For more details regarding qualification, please consult with your provider.
How can I start Esketamine Therapy?
- You can start the process by speaking with one of our medical assistants or your provider at your next visit.
Can Esketamine be taken with other antidepressants/medications?
- Yes, under the recommendations of your provider. Consult with your provider prior to undergoing Esketamine Therapy.
Is Esketamine Therapy covered by my insurance?
- Yes, we’re credentialed with and accept all major insurances. Insurance coverage and plans vary, our front office will work with your insurance provider to make sure you are covered and authorized to receive Esketamine treatment.
What happens if I miss a dose of Esketamine?
- If a patient misses a dose of Esketamine or is unable to attend one of their treatment sessions, they are advised to remain in their current dosing schedule. In the event that depressive symptoms worsen during this time, you will be able to discuss this with your provider how best to proceed and they will help you make any adjustments if necessary.
Can I pick up Spravato from the pharmacy and take it at home?
- No, Esketamine is administered via nasal spray under the supervision of one of our healthcare providers in office. You will be asked to remain at our treatment center for a period of two hours in order for us to monitor your response and potential side effects.
How many sessions are there?
- The amount of treatment sessions may vary depending on your reason for starting Esketamine Therapy. Typically the normal treatment schedule is 8 weeks.
- The first 4 weeks of Esketamine Therapy: This will consist of two treatment sessions per week.
- The final 4 weeks of Esketamine Therapy: This will consist of one treatment session per week.
- Additional treatment sessions may be required depending on your progression and response to treatment. This will be discussed between you and your provider throughout the treatment process to ensure quality of care.
How long is each treatment session?
- Each treatment session is two hours long. This will consist of the administration of Esketamine followed by a monitoring period to ensure your safety and track your progress throughout treatment.
Can I drive myself back to work after treatment?
- Patients are not advised to drive or operate heavy machinery for the remainder of the day following Esketamine Therapy. You will be asked in advance to have someone in place to pick you up after treatment sessions and are advised to rest for the remainder of the day.
Does it hurt?
- Esketamine Therapy does not hurt. It’s self administered in the form of a nasal spray under the supervision of one of our healthcare providers, there are no needles involved. Our staff will work with you closely to ensure your safety, autonomy, and quality of care during Esketamine Therapy.