Efficacy of Esketamine as Monotherapy for TRD:

https://clinicaltrials.gov/ct2/show/NCT04604210

NMDA Receptor Brain Signalling:

https://pmc.ncbi.nlm.nih.gov/articles/PMC5405628/

Efficacy and Safety of Esketamine + Oral Antidepressant:

https://pubmed.ncbi.nlm.nih.gov/31290965/

Patient Testimonials/Stories:

https://www.spravato.com/spravato-patient-stories/